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Lee DK Chang C. Endocrine mechanisms of disease: Expression and degradation of androgen

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Fragile X mental retardation protein (FMRP) is an RNA-binding protein important for the control of translation and synaptic function. The mutation or silencing of FMRP causes Fragile X syndrome (FXS). Small-Molecule-Mediated Degradation of the Androgen Receptor Through Hydrophobic Tagging. Androgen receptor (AR)-dependent transcription is a major driver of prostate tumor cell proliferation.

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